2,4'-dihydroxyacetophenone dioxygenase
In this article, we will approach 2,4'-dihydroxyacetophenone dioxygenase from different perspectives, with the aim of providing a comprehensive view on this topic/person/date. We will analyze its impact on today's society, its evolution over time and the possible implications it has in various areas. In addition, we will examine its relevance in the current context, as well as the different opinions and theories that exist in this regard. Through this comprehensive analysis, we aim to provide the reader with a more complete understanding of 2,4'-dihydroxyacetophenone dioxygenase and encourage reflection on its importance in our daily lives.
| 2,4'-dihydroxyacetophenone dioxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.13.11.41 | ||||||||
| CAS no. | 105503-64-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a 2,4'-dihydroxyacetophenone dioxygenase (EC 1.13.11.41) is an enzyme that catalyzes the chemical reaction
- 2,4'-dihydroxyacetophenone + O2 4-hydroxybenzoate + formate
Thus, the two substrates of this enzyme are 2,4'-dihydroxyacetophenone and O2, whereas its two products are 4-hydroxybenzoate and formate.
This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2. The systematic name of this enzyme class is 2,4'-dihydroxyacetophenone oxidoreductase (C-C-bond-cleaving). This enzyme is also called (4-hydroxybenzoyl)methanol oxygenase. This enzyme participates in bisphenol a degradation.[1]
References
- ^ Enya M, Aoyagi K, Hishikawa Y, Yoshimura A, Mitsukura K, Maruyama K (2012). "Molecular and catalytic properties of 2,4'-dihydroxyacetophenone dioxygenase from Burkholderia sp. AZ11". Bioscience, Biotechnology, and Biochemistry. 76 (3): 567–74. doi:10.1271/bbb.110867. PMID 22451401.
- Hopper DJ (October 1986). "Oxygenase properties of the (4-hydroxybenzoyl)methanol-cleavage enzyme from an Alcaligenes sp". The Biochemical Journal. 239 (2): 469–72. PMC 1147303. PMID 3814084.
