6-oxohexanoate dehydrogenase
In today's world, 6-oxohexanoate dehydrogenase has gained unprecedented relevance. Since its emergence, 6-oxohexanoate dehydrogenase has captured the attention and interest of a wide spectrum of society, generating debates, reflections and analysis in different areas. Both in the academic field and in the business world, 6-oxohexanoate dehydrogenase has been the subject of study and research, seeking to understand its impact and potential. In this article, we will explore various aspects related to 6-oxohexanoate dehydrogenase, from its origin to its current implications, with the aim of providing a broad and complete vision of this topic that is so relevant today.
| 6-oxohexanoate dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.2.1.63 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a 6-oxohexanoate dehydrogenase (EC 1.2.1.63) is an enzyme that catalyzes the chemical reaction
- 6-oxohexanoate + NADP+ + H2O adipate + NADPH + 2 H+
The 3 substrates of this enzyme are 6-oxohexanoate, NADP+, and H2O, whereas its 3 products are adipate, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 6-oxohexanoate:NADP+ oxidoreductase. This enzyme participates in caprolactam degradation.
References
 | This article includes a list of references, related reading, or external links, but its sources remain unclear because it lacks inline citations. (March 2016) |
- Davey JF, Trudgill PW (1977). "The metabolism of trans-cyclohexan-1,2-diol by an Acinetobacter species". Eur. J. Biochem. 74 (1): 115–27. doi:10.1111/j.1432-1033.1977.tb11373.x. PMID 856571.
- Donoghue NA, Trudgill PW (1975). "The metabolism of cyclohexanol by Acinetobacter NCIB 9871". Eur. J. Biochem. 60 (1): 1–7. doi:10.1111/j.1432-1033.1975.tb20968.x. PMID 1261.
