Acetylacetone-cleaving enzyme
In this article, we will delve into the fascinating world of Acetylacetone-cleaving enzyme, exploring its origins, impact and relevance today. Throughout history, Acetylacetone-cleaving enzyme has played a crucial role in various spheres of society, influencing both cultural development and technological advancement. Through a comprehensive analysis, we will examine how Acetylacetone-cleaving enzyme has shaped our perception of the world and generated fundamental debates around its relevance in the current context. From its origins to its future projection, this article aims to offer a comprehensive vision of Acetylacetone-cleaving enzyme, exploring its multiple facets and its impact on our daily lives.
| Acetylacetone-cleaving enzyme | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.13.11.50 | ||||||||
| CAS no. | 524047-53-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
In enzymology, an acetylacetone-cleaving enzyme (EC 1.13.11.50) is an enzyme that catalyzes the chemical reaction
- pentane-2,4-dione + O2 acetate + 2-oxopropanal
Thus, the two substrates of this enzyme are pentane-2,4-dione and O2, whereas its two products are acetate and 2-oxopropanal.
This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2. The systematic name of this enzyme class is acetylacetone:oxygen oxidoreductase. Other names in common use include Dke1, acetylacetone dioxygenase, diketone cleaving dioxygenase, and diketone cleaving enzyme.
References
- Straganz GD, Glieder A, Brecker L, Ribbons DW, Steiner W (2003). "Acetylacetone-cleaving enzyme Dke1: a novel C-C-bond-cleaving enzyme from Acinetobacter johnsonii". Biochem. J. 369 (Pt 3): 573–81. doi:10.1042/BJ20021047. PMC 1223103. PMID 12379146.
