Carotenoid-9',10'-cleaving dioxygenase

In this article, we will approach Carotenoid-9',10'-cleaving dioxygenase from different perspectives, with the purpose of offering a comprehensive and enriching vision of this topic or character. Along the following lines, we will explore its importance in today's society, as well as its impact in various areas, such as culture, economy, politics and daily life. In addition, we will delve into its evolution over time, its historical relevance and its influence in different contexts. Through detailed analysis, we aim to provide a deeper and more critical understanding of Carotenoid-9',10'-cleaving dioxygenase, in order to encourage constructive and informed reflection on this topic or character.

Carotenoid-9',10'-cleaving dioxygenase
Identifiers
EC no.1.13.11.71
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

Carotenoid-9',10'-cleaving dioxygenase (EC 1.13.11.71, BCO2 (gene), beta-carotene 9',10'-monooxygenase (misleading)) is an enzyme with systematic name all-trans-beta-carotene:O2 oxidoreductase (9',10'-cleaving).[1][2] This enzyme catalyses the following chemical reaction

all-trans-beta-carotene + O2 all-trans-10'-apo-beta-carotenal + beta-ionone

Carotenoid-9',10'-cleaving dioxygenase contains Fe2+.

References

  1. ^ Kiefer C, Hessel S, Lampert JM, Vogt K, Lederer MO, Breithaupt DE, von Lintig J (April 2001). "Identification and characterization of a mammalian enzyme catalyzing the asymmetric oxidative cleavage of provitamin A". The Journal of Biological Chemistry. 276 (17): 14110–6. doi:10.1074/jbc.M011510200. PMID 11278918.
  2. ^ Lindqvist A, He YG, Andersson S (November 2005). "Cell type-specific expression of beta-carotene 9',10'-monooxygenase in human tissues". The Journal of Histochemistry and Cytochemistry. 53 (11): 1403–12. doi:10.1369/jhc.5A6705.2005. PMID 15983114.