Propionate—CoA ligase
In today's article we are going to talk about Propionate—CoA ligase, a topic that has gained great relevance in recent years. Propionate—CoA ligase is a topic that has aroused the interest of experts and people of all ages, since its impact extends to various areas of society. Throughout this article, we will explore different aspects related to Propionate—CoA ligase, analyzing its history, its influence today and possible future prospects. Furthermore, we will try to offer a global vision that allows the reader to understand the importance of this topic in today's society.
| Propionate—CoA ligase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 6.2.1.17 | ||||||||
| CAS no. | 55326-49-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a propionate—CoA ligase (EC 6.2.1.17) is an enzyme that catalyzes the chemical reaction
- ATP + propanoate + CoA AMP + diphosphate + propanoyl-CoA
The 3 substrates of this enzyme are ATP, propanoate, and CoA, whereas its 3 products are AMP, diphosphate, and propanoyl-CoA.
This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is propanoate:CoA ligase (AMP-forming). This enzyme is also called propionyl-CoA synthetase. This enzyme participates in propanoate metabolism.
References
- Ricks CA, Cook RM (1981). "Regulation of volatile fatty acid uptake by mitochondrial acyl CoA synthetases of bovine liver". Journal of Dairy Science. 64 (12): 2324–35. doi:10.3168/jds.S0022-0302(81)82854-8. PMID 7341659.
