Sorbose 5-dehydrogenase (NADP+)

In this article, we will thoroughly explore the impact of Sorbose 5-dehydrogenase (NADP+) on our lives. From its origins to its relevance today, Sorbose 5-dehydrogenase (NADP+) has become a topic of great interest to researchers, academics and the general public. Over the years, Sorbose 5-dehydrogenase (NADP+) has generated debates, discussions and different perspectives that have enriched our understanding of this phenomenon. Through this comprehensive analysis, we will seek to shed light on the various aspects of Sorbose 5-dehydrogenase (NADP+) and how it has shaped our lives on different levels. This article will be a complete guide for those who wish to delve into the fascinating world of Sorbose 5-dehydrogenase (NADP+) and understand its importance in our contemporary society.

sorbose 5-dehydrogenase (NADP+)
Identifiers
EC no.1.1.1.123
CAS no.37250-52-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a sorbose 5-dehydrogenase (NADP+) (EC 1.1.1.123) is an enzyme that catalyzes the chemical reaction

L-sorbose + NADP+ 5-dehydro-D-fructose + NADPH + H+

Thus, the two substrates of this enzyme are L-sorbose and NADP+, whereas its 3 products are 5-dehydro-D-fructose, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-sorbose:NADP+ 5-oxidoreductase. Other names in common use include 5-ketofructose reductase, 5-keto-D-fructose reductase, sorbose (nicotinamide adenine dinucleotide phosphate) dehydrogenase, reduced nicotinamide adenine dinucleotide phosphate-linked, reductase, and sorbose 5-dehydrogenase (NADP+).

References

  • Englard S, Kaysen G, Avigad G (1970). "5-keto-D-fructose. VI. A specific reduced nicotinamide adenine dinucleotide phosphate-linked reductase from yeast". J. Biol. Chem. 245 (6): 1311–8. PMID 4392628.