Valine dehydrogenase (NADP+)
In today's world, Valine dehydrogenase (NADP+) is a topic that has captured the attention of numerous individuals and experts in various fields. Since its emergence, Valine dehydrogenase (NADP+) has generated great interest and has been the subject of numerous studies, research and debates. This phenomenon has aroused both curiosity and fear in many people, since its impact on different aspects of modern life is undeniable. Valine dehydrogenase (NADP+) has proven to be a relevant and extremely significant topic in our contemporary society, and its influence only seems to be constantly growing. In this article, we will thoroughly explore the various facets of Valine dehydrogenase (NADP+) and analyze its impact in different areas, offering a comprehensive and insightful view on this topic that is so relevant today.
| valine dehydrogenase (NADP) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.4.1.8 | ||||||||
| CAS no. | 37255-39-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a valine dehydrogenase (NADP+) (EC 1.4.1.8) is an enzyme that catalyzes the chemical reaction
- L-valine + H2O + NADP+ 3-methyl-2-oxobutanoate + NH3 + NADPH + H+
The 3 substrates of this enzyme are L-valine, H2O, and NADP+, whereas its 4 products are 3-methyl-2-oxobutanoate, NH3, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-valine:NADP+ oxidoreductase (deaminating). Other names in common use include valine dehydrogenase (nicotinamide adenine dinucleotide phosphate), and valine dehydrogenase (NADP+).
References
- Kagan ZS, Kretovich WL, Polyakov WA (1966). "Biosynthesis of valine by reductive amination of its keto analogue in plants". Enzymologia. 30 (6): 343–66. PMID 6005410.
- Kagan ZS, Poliakov VA, Kretovich VL (1968). "". Biokhimiia. 33 (1): 89–96. PMID 4385962.
- Kagan ZS, Poliakov VA, Kretovich VL (1969). "". Biokhimiia. 34 (1): 59–65. PMID 4389825.
- Behal V; Vancura, A; Volc, J; Neuzil, J; Flieger, M; Basarová, G; Bĕhal, V (1988). "Isolation and characterization of valine dehydrogenase from Streptomyces aureofaciens". J. Bacteriol. 170 (11): 5192–6. doi:10.1128/jb.170.11.5192-5196.1988. PMC 211589. PMID 3182727.
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