(tyrosine 3-monooxygenase) kinase
In today's article, we are going to delve into the exciting world of (tyrosine 3-monooxygenase) kinase. Whether you are an expert in the field or just beginning to explore this topic, you will find valuable information that will help you expand your knowledge. From the history and evolution of (tyrosine 3-monooxygenase) kinase to practical applications in daily life, here we will address all aspects of this topic. Additionally, we will explore the latest trends and discoveries that are revolutionizing (tyrosine 3-monooxygenase) kinase. So get ready to immerse yourself in a journey full of learning and discoveries about (tyrosine 3-monooxygenase) kinase.
In enzymology, a kinase (EC 2.7.11.6) is an enzyme that catalyzes the chemical reaction
- ATP + ADP + phospho-
Thus, the two substrates of this enzyme are ATP and tyrosine 3-monooxygenase, whereas its two products are ADP and phospho-(tyrosine-3-monooxygenase).
This enzyme belongs to the family of transferases, specifically those transferring a phosphate group to the sidechain oxygen atom of serine or threonine residues in proteins (protein-serine/threonine kinases). The systematic name of this enzyme class is ATP: phosphotransferase. Other names in common use include pheochromocytoma tyrosine hydroxylase-associated kinase, STK4, and tyrosine 3-monooxygenase kinase (phosphorylating). This enzyme participates in MAPK signaling pathway and non-small cell lung cancer.
References
- Pigeon D, Drissi-Daoudi R, Gros F, Thibault J (1986). "". Comptes Rendus de l'Académie des Sciences, Série III. 302 (12): 435–8. PMID 2872947.
- Pigeon D, Ferrara P, Gros F, Thibault J (1987). "Rat pheochromocytoma tyrosine hydroxylase is phosphorylated on serine 40 by an associated protein kinase". J. Biol. Chem. 262 (13): 6155–8. PMID 2883182.
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