Ciliary neurotrophic factor receptor
In this article we will explore the fascinating world of Ciliary neurotrophic factor receptor and all the different facets that make it up. From its origin and evolution to its impact on today's society, we will immerse ourselves in a journey of discovery and learning. We will analyze its implications in various fields, from science and technology to arts and culture. With a critical and reflective look, we will delve into the positive and negative aspects of Ciliary neurotrophic factor receptor, as well as its influence on our daily lives. Join us on this tour and discover everything there is to know about Ciliary neurotrophic factor receptor.
| ciliary neurotrophic factor receptor | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | CNTFR | ||||||
| NCBI gene | 1271 | ||||||
| HGNC | 2170 | ||||||
| OMIM | 118946 | ||||||
| RefSeq | NM_001842 | ||||||
| UniProt | P26992 | ||||||
| Other data | |||||||
| Locus | Chr. 9 p13 | ||||||
| |||||||
The ciliary neurotrophic factor receptor, also known as CNTFR, binds the ciliary neurotrophic factor. This receptor and its cognate ligand support the survival of neurons.[1] This receptor is most closely related to the interleukin-6 receptor. This receptor possesses an unusual attachment to the cell membrane through a glycophosphatidylinositol linkage.[2]
References
- ^ Davis S, Aldrich TH, Valenzuela DM, Wong VV, Furth ME, Squinto SP, Yancopoulos GD (1991). "The receptor for ciliary neurotrophic factor". Science. 253 (5015): 59–63. Bibcode:1991Sci...253...59D. doi:10.1126/science.1648265. PMID 1648265.
- ^ Sleeman MW, Anderson KD, Lambert PD, Yancopoulos GD, Wiegand SJ (2000). "The ciliary neurotrophic factor and its receptor, CNTFR alpha". Pharm Acta Helv. 74 (2–3): 265–72. doi:10.1016/S0031-6865(99)00050-3. PMID 10812968.
External links
- Ciliary+Neurotrophic+Factor+Receptor+alpha+Subunit at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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