Didesmethylcitalopram

Nowadays, Didesmethylcitalopram has become a topic of great relevance and interest in different areas. From politics to science, culture and technology, Didesmethylcitalopram has captured the attention of millions of people around the world. Its implications are profound and its influence is felt in every aspect of daily life. In this article, we will take a closer look at the different facets of Didesmethylcitalopram and how it has impacted our society. From its origins to its contemporary evolution, we will delve into an area of ​​knowledge or an aspect of reality that leaves no one indifferent. Join us on this tour of Didesmethylcitalopram and discover everything behind this phenomenon.

Didesmethylcitalopram
Clinical data
ATC code
  • none
Legal status
Legal status
  • In general: uncontrolled
Pharmacokinetic data
Elimination half-life100 h
Identifiers
  • (RS or S)-1--1-
    (4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile
CAS Number
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC18H17FN2O
Molar mass296.345 g·mol−1
3D model (JSmol)
  • c1cc(ccc12(c3ccc(cc3CO2)C#N)CCCN)F
  • InChI=1S/C18H17FN2O/c19-16-5-3-15(4-6-16)18(8-1-9-20)17-7-2-13(11-21)10-14(17)12-22-18/h2-7,10H,1,8-9,12,20H2/t18-/m0/s1 ☒N
  • Key:RKUKMUWCRLRPEJ-SFHVURJKSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Didesmethylcitalopram is an active metabolite of the antidepressant drug citalopram (racemic).[1] Didesmethylescitalopram is an active metabolite of the antidepressant escitalopram, the S-enantiomer of citalopram. Like citalopram and escitalopram, didesmethyl(es)citalopram functions as a selective serotonin reuptake inhibitor (SSRI), and is responsible for some of its parents' therapeutic benefits.

See also

References

  1. ^ Rop PP, Durand A, Viala A, Jørgensen A (April 1990). "Simultaneous determination of citalopram, monodesmethylcitalopram and didesmethylcitalopram in plasma by high-performance liquid chromatography after column extraction". Journal of Chromatography. 527 (1): 226–32. doi:10.1016/s0378-4347(00)82105-2. PMID 2365786.
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