In this article we are going to analyze LILRB3 in detail, a topic that has gained relevance in recent times. It is important to understand the importance of LILRB3 in various spheres of daily life, since its influence is considerable in aspects such as health, economics, politics, technology and culture. Along these lines we will explore the different facets of LILRB3, as well as its implications in today's world. From its origin to its possible future developments, we will delve into an exhaustive analysis that will allow us to better understand the role that LILRB3 plays in the contemporary world.
Leukocyte immunoglobulin-like receptor subfamily B member 3 is a protein that in humans is encoded by the LILRB3gene.[4][5][6]
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells and is believed to be a myeloid checkpoint. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.[6]
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