Names | |
---|---|
Preferred IUPAC name N,N-Diethyl-N-methyl-3-anilinium iodide | |
Other names AR-16, TL-1217 | |
Identifiers | |
CAS Number | |
3D model (JSmol) | |
ChemSpider | |
PubChem CID | |
CompTox Dashboard (EPA) | |
InChI
| |
SMILES
| |
Properties | |
Chemical formula | C13H21IN2O2 |
Molar mass | 364.227 g·mol−1 |
Related compounds | |
Related compounds | Neostigmine Miotine |
Hazards | |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose) | 129 μg/kg (Subcutaneous, mice) 75 μg/kg (Subcutaneous, cats) 75 μg/kg (Subcutaneous, dogs) 150 μg/kg (Subcutaneous, rabbits) 122.5 μg/kg (Intramuscular, rats) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references |
T-1123 is a carbamate-based acetylcholinesterase inhibitor. It was investigated as a chemical warfare agent starting in 1940. It does not go through the blood-brain barrier due to the charge on quaternary nitrogen. The antidote is atropine. T-1123 is a quaternary ammonium ion. A phenyl carbamate ester is bonded in the meta position to the nitrogen on a diethylmethyl amine. The chloride and methylsulfate salt of T-1123 is TL-1299 and TL-1317, respectively.
T-1123 can be produced from m-diethylaminophenol, methyl isocyanate and methyl iodide. First, m-diethylaminophenol is reacted with methyl isocyanate to produce a methylcarbamate. The resulting methylcarbamate is then reacted with methyl iodide to produce T-1123.
Neurotoxins | |
---|---|
Animal toxins | |
Bacterial | |
Cyanotoxins | |
Plant toxins | |
Mycotoxins | |
Pesticides | |
Nerve agents | |
Bicyclic phosphates | |
Cholinergic neurotoxins | |
Other |
Acetylcholine metabolism and transport modulators | |||||||
---|---|---|---|---|---|---|---|
Enzyme (modulators) |
| ||||||
Transporter (modulators) |
| ||||||
Release (modulators) |
| ||||||
See also Receptor/signaling modulators Muscarinic acetylcholine receptor modulators Nicotinic acetylcholine receptor modulators |
This article about an organic compound is a stub. You can help Wikipedia by expanding it. |